2019-6-27 · CHAPS is a zwitterionic surfactant used in the laboratory to solubilize biological macromolecules such as proteins.It may be synthesized from cholic acid and is zwitterionic due to its quaternary ammonium and sulfonate groups; it is structurally similar to certain bile acids, such as taurodeoxycholic acid and taurochenodeoxycholic acid.It is used as a non-denaturing detergent in the …